NerveSoothe vs NerveRevive 360: Best Neuropathy Supplement in 2026?
Both NerveSoothe and NerveRevive 360 are ClickBank neuropathy supplements targeting the same core problem: the tingling, burning, and numbness that comes with diabetic peripheral neuropathy. They draw from the same research base, share a similar ingredient philosophy, and both come backed by a 60-day money-back guarantee. So how do you choose between them?
The honest answer is that ingredient differentiation is the only meaningful framework for making this call. Marketing copy is nearly identical across this category. What matters is what is actually on the label — the specific compounds, their forms, and their doses relative to what peer-reviewed research considers therapeutic. That is what this comparison covers.
TL;DR — Quick Comparison
- Both NerveSoothe and NerveRevive 360 are ALA + B-vitamin formulas targeting diabetic peripheral neuropathy symptoms.
- NerveSoothe (vendor: NERVESOOTH, sold at getnervesoothe.com) has higher ClickBank gravity, suggesting stronger sales history and more user feedback.
- NerveRevive 360 (vendor: KANR3) has a lower gravity score (~0.2), indicating a newer or lower-volume product.
- Both carry 60-day money-back guarantees through ClickBank — meaningful buyer protection in this category.
- Our edge pick: NerveSoothe, based on market traction and clear ALA-forward positioning — but verify the current label on both before purchasing.
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1. What Each Supplement Is
Before getting into the ingredient science, it helps to understand what each product actually is and who makes it.
NerveSoothe
NerveSoothe is sold by the vendor NERVESOOTH on ClickBank and is available through getnervesoothe.com. It positions itself as a nutritional support formula specifically for people experiencing diabetic peripheral neuropathy — the condition where chronically elevated blood sugar damages the small nerve fibers in the feet, legs, and hands over time.
The core claim is not curative. Like most responsible formulations in this category, NerveSoothe frames its role as nutritional support — providing the specific micronutrients that research has associated with nerve function, myelin health, and reduction of oxidative stress in nerve tissue. The formula centers on alpha lipoic acid (ALA), the compound with the most clinical trial evidence in this indication, combined with the B-vitamin complex that supports nerve structure and function.
NerveSoothe’s higher ClickBank gravity score suggests it has generated meaningful sales volume — which matters in this context not because popularity equals quality, but because it means more real-world users have had the chance to report their experiences, both positive and negative. There is simply more signal available to draw from.
NerveRevive 360
NerveRevive 360 is sold by vendor KANR3 on ClickBank. It targets the same primary audience — people with type 2 diabetes experiencing peripheral neuropathy symptoms — and builds its formula around the same foundational compounds: ALA and B vitamins.
The product has a ClickBank gravity score of approximately 0.2 at the time of this writing, which is notably lower than NerveSoothe’s. In ClickBank’s gravity metric, higher scores reflect more recent sales through distinct affiliates. A low gravity score does not necessarily indicate a poor product — it may simply mean the product is newer, is marketed more narrowly, or relies less on affiliate traffic. But it does mean there is less external validation signal available.
Both products share the same ClickBank infrastructure, which is relevant for buyer protection purposes. ClickBank enforces its 60-day refund policy across all vendors on its platform — so regardless of which you choose, that floor-level protection applies.
Who Both Products Are For
The shared target audience for NerveSoothe and NerveRevive 360 is fairly specific:
- Adults with type 2 diabetes who have been diagnosed with or suspect peripheral neuropathy
- People experiencing symptoms like burning pain, tingling, numbness, electric-shock sensations, or impaired sensation in the feet and lower legs
- Those who have not found adequate relief through conventional management alone and are exploring nutritional support options
- People taking metformin (which depletes B12 over time, making B12 supplementation particularly relevant)
- Anyone who wants to support nerve health proactively given a diabetes diagnosis
If you do not have diabetes or a documented history of blood sugar dysregulation, these products are still in a plausible nutritional category — but they are clearly formulated with the diabetic neuropathy population in mind.
2. The Evidence Base They’re Both Built On
Understanding why ALA and B vitamins are the dominant ingredients in neuropathy supplements requires a brief look at the research. Both NerveSoothe and NerveRevive 360 are drawing from the same scientific well. Here is what that well actually contains.
Alpha Lipoic Acid: The Anchor Compound
Alpha lipoic acid is a naturally occurring antioxidant that is both water- and fat-soluble, which gives it unusual access to both aqueous and lipid environments in the body — including nerve cell membranes. In diabetic peripheral neuropathy, chronic hyperglycemia creates excessive oxidative stress in nerve tissue, damaging mitochondria and impairing nerve conduction. ALA’s proposed mechanism is to quench this oxidative damage and improve mitochondrial function in affected nerve cells.
The clinical trial record on ALA for diabetic neuropathy is the strongest in the supplement category. The key studies:
ALADIN Trial (Alpha Lipoic Acid in Diabetic Neuropathy): Published in Diabetologia (Ziegler et al., 1995), this randomized controlled trial used intravenous ALA at 600mg/day for three weeks and showed significant improvements in the Total Symptom Score (TSS) — a composite measure of neuropathy severity — compared to placebo. This was the landmark trial that established ALA’s therapeutic potential in this indication.
SYDNEY 2 Trial (Sensory Symptoms in Diabetic Neuropathy): Published in Diabetes Care (Ziegler et al., 2006), this five-week RCT used oral ALA at 600mg/day and demonstrated statistically significant reductions in TSS compared to placebo. This is the pivotal trial for oral ALA supplementation — the delivery method used in both NerveSoothe and NerveRevive 360. The 600mg/day dose has become the research benchmark.
NATHAN 1 Trial: A four-year study examining whether oral ALA (600mg/day) could slow the progression of diabetic neuropathy. Results showed a trend toward slowed progression in clinical measures, though the primary endpoint was not statistically significant. However, neurophysiology measures and secondary endpoints supported ALA’s effect on nerve function over time.
The consistent finding across this research base is that 600mg/day of ALA is the dose at which effects on neuropathy symptoms and nerve conduction velocity become measurable. This is the benchmark against which any neuropathy supplement’s ALA dose should be evaluated.
The ALA Form Question: R-ALA vs. R/S-ALA
Commercial ALA is typically sold in two forms: racemic (R/S-ALA, a 50/50 mix of R and S isomers) or pure R-ALA. The R-form is the biologically active isomer — the S-form is essentially inert from a therapeutic standpoint. This means that if a product uses racemic ALA, the effective therapeutic dose is roughly half the stated dose.
A product listing 600mg of racemic ALA is delivering approximately 300mg of biologically active R-ALA. A product listing 300mg of pure R-ALA is delivering the same active dose at half the stated milligrams. This is one of the most important label details to check — and one of the most commonly obscured in marketing materials.
Benfotiamine: Why B1 Form Matters for Neuropathy
Standard thiamine (vitamin B1) has poor bioavailability — oral absorption is limited and actively constrained by intestinal transporters. Benfotiamine is a fat-soluble thiamine derivative that bypasses these limitations, achieving tissue concentrations of thiamine approximately three to five times higher than standard oral thiamine at equivalent doses.
For diabetic neuropathy specifically, this matters beyond just thiamine’s general role in nerve function. Benfotiamine inhibits the formation of advanced glycation end-products (AGEs) — the sugar-protein compounds that accumulate in diabetes and contribute directly to microvascular and nerve damage. Published research (Experimental and Clinical Endocrinology & Diabetes, Stracke et al., 2008) has shown benfotiamine supplementation reduces AGE burden in diabetic patients. Standard thiamine does not demonstrate this effect at achievable oral doses.
When evaluating any neuropathy supplement label, look specifically for the word “benfotiamine” rather than just “thiamine” or “vitamin B1.” The difference is clinically meaningful.
Methylcobalamin: The Right Form of B12
Vitamin B12 is essential for myelin sheath integrity — the protective coating around nerve fibers that enables efficient signal conduction. In peripheral neuropathy, myelin degradation is part of the damage picture. B12 deficiency accelerates this, and metformin (the first-line medication for type 2 diabetes) is well-documented to deplete B12 over time through interference with intrinsic factor and ileal B12 absorption.
Methylcobalamin is the neurologically active form of B12 — it is directly usable by nerve tissue without requiring metabolic conversion. Cyanocobalamin, the far cheaper and more common form, must be converted to methylcobalamin by the liver before it can be used by nerve cells. For healthy individuals, this conversion is generally adequate. For people with metabolic compromise or high supplementation needs, methylcobalamin is the preferred form.
Research published in Muscle & Nerve (Yaqub et al., 1992) found that high-dose methylcobalamin (1,500 mcg/day) improved nerve conduction velocity and neuropathy symptoms in diabetic patients over 24 weeks — an effect not consistently demonstrated with cyanocobalamin at standard doses.
The Four Label Questions for Any Neuropathy Supplement
Based on this research landscape, here are the four questions that separate a well-constructed neuropathy supplement from a loosely assembled vitamin stack:
- What is the ALA dose? Look for 600mg/day as the research benchmark.
- Is it R-ALA or R/S-ALA? R-form is more bioavailable; racemic at 600mg delivers only ~300mg of active R-ALA.
- Is B1 benfotiamine or standard thiamine? Benfotiamine is preferred for AGE reduction and superior tissue uptake.
- Is B12 methylcobalamin or cyanocobalamin? Methylcobalamin is directly usable by nerve tissue and preferred for this indication.
These four questions apply equally to NerveSoothe and NerveRevive 360. Use them when you review each product’s current label.
3. Ingredient Comparison
Both products are built on the same foundational science. The differentiation — when it exists — is in the specific forms chosen, the doses used, and what additional compounds (if any) each formula includes. The table below frames the comparison using the research standards established above.
Important transparency note: Supplement formulas can change. The information below reflects available label data at the time of writing. Always verify the current label on each product’s official site before purchasing.
| Ingredient | NerveSoothe | NerveRevive 360 | Research Standard |
|---|---|---|---|
| Alpha Lipoic Acid | Present — verify current dose | Present — verify current dose | 600mg/day |
| ALA Form | Verify: R-ALA or R/S-ALA | Verify: R-ALA or R/S-ALA | R-ALA preferred |
| Vitamin B1 Form | Verify: Benfotiamine or Thiamine | Verify: Benfotiamine or Thiamine | Benfotiamine preferred |
| Vitamin B12 Form | Verify: Methylcobalamin or Cyanocobalamin | Verify: Methylcobalamin or Cyanocobalamin | Methylcobalamin preferred |
| Additional compounds | Verify on current label | Verify on current label | — |
| Capsules per bottle | 60 (typical) | 60 (typical) | 30-day supply at 2/day |
| Serving size | 2 capsules/day (typical) | 2 capsules/day (typical) | — |
How to Use This Table
The value of this comparison framework is not the specific numbers — it is the questions it trains you to ask. When you land on either product’s official page, go directly to the Supplement Facts panel. Run through the four questions above. Specifically:
- If the ALA dose is below 300mg of R-ALA (or below 600mg of racemic ALA), the product is underdosed relative to the clinical trials that established its effectiveness.
- If B1 is listed simply as “Thiamine HCl” or “Thiamine Mononitrate” rather than “Benfotiamine,” you are getting the less bioavailable, less AGE-inhibiting form.
- If B12 is listed as “Cyanocobalamin” rather than “Methylcobalamin,” the neurological benefit is less direct and less certain.
Both NerveSoothe and NerveRevive 360 operate in the ALA + B-vitamin category. NerveSoothe’s positioning language places particular emphasis on ALA as its core compound — consistent with the most robustly evidenced ingredient in the category. The more clearly a product centers its ALA dose and form, the more confident you can be that its formula is built around the research rather than around a broad nutritional scattershot approach.
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4. Price Comparison
Pricing in this category is fairly standardized across ClickBank vendors, and both NerveSoothe and NerveRevive 360 follow the typical multi-bottle discount structure.
| NerveSoothe | NerveRevive 360 | |
|---|---|---|
| Single bottle | ~$49–$69 | ~$49–$69 |
| 3-bottle bundle | Discount available | Discount available |
| Best value (6-bottle) | Largest per-bottle discount | Largest per-bottle discount |
| Shipping | Check current offer | Check current offer |
| Guarantee | 60-day money-back | 60-day money-back |
What the pricing structure means in practice: Both products are priced comparably at the single-bottle level. The real differentiation in value comes from the multi-bottle bundles, which both vendors use to encourage longer commitment periods. This is relevant because neuropathy supplementation — based on the research timeline — benefits from at least 8–12 weeks of consistent use before you can draw meaningful conclusions about individual response. A three-bottle supply covers that window.
The 6-bottle option is typically positioned as the “best value” by both vendors. This makes sense economically if you are committed to a full trial period, but we generally recommend starting with the 3-bottle option — it gives you the full evaluation window without over-committing before you know how your body responds.
Pricing caveat: ClickBank supplement pricing is subject to promotional changes. The ranges above reflect typical positioning; verify current pricing on each product’s official site before purchasing.
The 60-day money-back guarantee applies to both products through ClickBank’s platform-level buyer protection. This is not a vendor-by-vendor policy — it is enforced by ClickBank as a condition of selling on their platform. If either product does not deliver what you hoped within 60 days, you can request a refund through ClickBank’s customer service portal regardless of what the vendor’s own site says.
5. Brand Transparency Comparison
In the supplement industry, brand transparency is genuinely difficult to assess from the outside. Neither NerveSoothe nor NerveRevive 360 is a pharmaceutical company with regulatory filings and clinical trial registrations on record. Both are ClickBank supplement vendors. Here is what can be assessed with available information.
NerveSoothe (Vendor: NERVESOOTH)
- ClickBank vendor ID: NERVESOOTH
- Official site: getnervesoothe.com
- ClickBank gravity: Higher than NerveRevive 360 (gravity reflects recent affiliate-driven sales volume)
- Market presence: The higher gravity score indicates a more established market position — more affiliates have made recent sales, which means more consumer exposure and feedback
ClickBank gravity is an imperfect proxy for trust, but it is one of the few measurable signals available in this market segment. A higher gravity indicates that real buyers have been purchasing, that the vendor’s sales process converts, and that there is at least some real-world feedback signal from those purchases. NerveSoothe’s gravity suggests it has been on the market long enough to accumulate meaningful sales history.
NerveRevive 360 (Vendor: KANR3)
- ClickBank vendor ID: KANR3
- ClickBank gravity: Approximately 0.2 at time of writing
- Market presence: Lower gravity suggests a newer product, narrower affiliate reach, or lower overall sales volume
A gravity score of 0.2 is on the low end for an active ClickBank product. This does not mean NerveRevive 360 is a poor product — many high-quality supplements have low ClickBank gravity because they are newer or because the vendor does not rely heavily on affiliate traffic. But it does mean there is less third-party validation signal available. Fewer purchases means fewer consumer reviews, less community discussion, and less data about real-world user experience.
What ClickBank Buyer Protection Covers
For both products, ClickBank’s 60-day refund policy is the floor-level protection that applies regardless of brand transparency. If you purchase either product through official ClickBank channels and are dissatisfied within 60 days, you are entitled to a refund. This is meaningful protection in a category where products cannot be clinically validated in advance by individual consumers.
The practical implication: whatever transparency gap exists between NerveSoothe and NerveRevive 360 is partially mitigated by this shared buyer protection infrastructure. You are not fully exposed to brand-level trust uncertainty when the purchase platform itself enforces refunds.
6. Who Each Product Is Better For
Given everything above, here is a practical breakdown of which product may suit which buyer.
NerveSoothe May Be a Better Fit If You:
- Want an established neuropathy supplement with more real-world purchase history to draw from
- Prefer an ALA-forward formulation with clear positioning on the primary evidenced ingredient
- Are making your first purchase in this supplement category and want the product with more market signal behind it
- Have found other neuropathy supplements underwhelming and want to try the option with greater traction in its category
- Value the combination of ClickBank buyer protection AND a product with enough sales history to have generated meaningful consumer feedback
NerveRevive 360 May Be a Better Fit If You:
- Have already tried NerveSoothe for a full 8–12 week trial without satisfactory results and want to try a different formulation
- Are specifically drawn to the KANR3 vendor’s formula based on your own label comparison using the four-question framework above
- Want to trial a newer product and are comfortable with the lower feedback volume
- Are doing a systematic comparison of every major ClickBank neuropathy supplement and want to evaluate both side-by-side
The common thread in both cases: use the ingredient label as your primary decision tool, not marketing language. If NerveRevive 360’s current label shows superior ALA form and dose, benfotiamine B1, and methylcobalamin B12, it may be the better formulation regardless of gravity score. Conversely, if NerveSoothe’s label more closely matches the research benchmarks, that edge is meaningful.
7. What Neither Supplement Replaces
This section is non-negotiable for anyone considering nutritional supplementation for diabetic peripheral neuropathy. Both NerveSoothe and NerveRevive 360 are nutritional support tools. They operate in a supporting role — not a primary treatment role.
Blood Sugar Control Remains the Primary Intervention
Diabetic peripheral neuropathy is, at its root, a consequence of chronic hyperglycemia. The nerve damage accumulates over time when blood sugar is consistently poorly controlled. No supplement can reverse the cause while the cause is ongoing. The most important thing you can do for diabetic neuropathy is work with your healthcare provider to achieve and maintain stable blood sugar — through medication, dietary changes, physical activity, and weight management as appropriate.
The ALA research cited above (ALADIN, SYDNEY 2) was conducted in populations who were also receiving standard diabetic management. ALA’s benefits in those trials were observed on top of — not instead of — appropriate medical care.
Lifestyle Foundations
The three lifestyle factors with the strongest evidence base for slowing neuropathy progression are:
Diet: Reduction of refined carbohydrates and processed sugars to lower glycemic variability. Anti-inflammatory dietary patterns (Mediterranean-style or whole-food-based) are associated with reduced neuropathy severity in observational data.
Exercise: Aerobic exercise improves peripheral circulation and has been shown in multiple studies to reduce neuropathy symptoms — particularly in the feet and lower legs. Even walking 30 minutes daily has measurable effects on nerve conduction over time.
Weight management: Reducing excess body weight reduces mechanical load on the feet and improves insulin sensitivity, both of which have downstream benefits for peripheral nerve health.
No supplement, however well-formulated, substitutes for these foundations.
When to Seek Neurological Evaluation
If your neuropathy symptoms are:
- Rapidly worsening over weeks rather than stable over months
- Accompanied by significant muscle weakness or difficulty walking
- Present without a clear metabolic explanation (you have normal blood sugar but unexplained neuropathy)
- Associated with falls, skin breakdown, or foot ulceration
…these are indications for neurological evaluation — not supplementation. Peripheral neuropathy can have many causes beyond diabetes, and some of those causes require specific medical intervention. Please work with your healthcare provider for these situations. This article discusses nutritional support for already-diagnosed diabetic peripheral neuropathy — not evaluation, diagnosis, or treatment of neuropathy symptoms.
8. Our Recommendation
After weighing both products against the four-question ingredient framework, the pricing structure, buyer protection, and available transparency signals, our assessment is:
NerveSoothe holds a slight but meaningful edge.
The reasoning is straightforward:
Market signal matters in this category. NerveSoothe’s higher ClickBank gravity indicates a more established product with a larger real-world user base. This is the closest available proxy for aggregate consumer feedback in a market where independent clinical trials on specific branded products do not exist.
ALA-forward positioning is appropriate. NerveSoothe’s marketing centers ALA as its primary ingredient — consistent with where the strongest clinical evidence sits. Products that lead with their most evidenced compound signal better formulation discipline than those that lead with secondary or more speculative ingredients.
Both have equivalent buyer protection. The 60-day ClickBank guarantee means the downside on either choice is capped. If NerveSoothe does not deliver what you hoped within 60 days, you are entitled to a refund. This makes the decision lower-stakes than it might otherwise feel.
The transparent caveat: We cannot verify the current label of either product and neither should you take any review’s word for it — including this one. Before purchasing, visit getnervesoothe.com and the NerveRevive 360 official site, pull up both Supplement Facts panels, and run the four questions. If NerveRevive 360’s label is more closely aligned with the research benchmarks on this specific comparison, that finding should override any recommendation based on secondary signals like gravity.
That said, for a buyer making a first purchase in this category without the time or inclination to do a detailed label comparison, NerveSoothe is the safer default choice based on available information.
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If you have already tried NerveSoothe without success, NerveRevive 360 is a reasonable second option to evaluate:
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9. Frequently Asked Questions
What is the difference between NerveSoothe and NerveRevive 360?
Both target diabetic peripheral neuropathy with ALA and B-vitamin based formulas. The differences lie in specific ingredient forms, additional compounds, dosing, and price structure. Both are sold through ClickBank with a 60-day guarantee. NerveSoothe has a higher ClickBank gravity score, indicating more established sales history, while NerveRevive 360 has a gravity of approximately 0.2, suggesting a newer or lower-volume product.
Which is better for neuropathy — NerveSoothe or NerveRevive 360?
Both have plausible formulations for neuropathy support. The choice depends on ingredient preferences, price-per-serving, and individual response. We recommend comparing label details — particularly ALA dose and whether B1 is benfotiamine vs. standard thiamine, and whether B12 is methylcobalamin vs. cyanocobalamin. NerveSoothe holds a slight edge based on market traction and ALA-forward positioning, but label comparison should be the deciding factor.
Can you take NerveSoothe and NerveRevive 360 together?
No. Both contain high levels of the same nutrients (ALA, B vitamins). Combining them could lead to excessive doses without added benefit and increases side effect risk — particularly for ALA, which at very high doses can cause GI distress and, in rare cases, interfere with thyroid function. Choose one product and use it consistently for 8+ weeks before evaluating its effect.
Do both NerveSoothe and NerveRevive 360 have a money-back guarantee?
Yes. Both are sold through ClickBank, which enforces a 60-day money-back guarantee on both products. This is a platform-level policy — you can request a refund through ClickBank’s customer service regardless of what the individual vendor’s site states.
How long should I take a neuropathy supplement before seeing results?
Clinical research on ALA for neuropathy gives us a reasonable benchmark: the SYDNEY 2 trial showed measurable improvements in Total Symptom Score over five weeks of oral ALA at 600mg/day; the ALADIN trial showed effects with intravenous ALA at three weeks. For oral supplementation in a real-world context — where absorption is more variable — most practitioners who work with these protocols recommend 8–12 weeks of consistent supplementation before drawing conclusions. Individual variation is significant in this area.
What does clinical evidence say about ALA for neuropathy?
Alpha lipoic acid has the strongest evidence base of all supplements for diabetic peripheral neuropathy. Multiple randomized controlled trials — including the ALADIN series and the SYDNEY 2 trial — show significant reductions in total symptom score (TSS) and, in longer-duration studies, improvements in nerve conduction velocity. The research benchmark is 600mg/day ALA, with multiple trials using this dose. The evidence is strong enough that ALA is listed as a treatment option for diabetic neuropathy in several European clinical practice guidelines, though it remains outside most US guidelines as a standard recommendation.
Is NerveRevive 360 a scam?
NerveRevive 360 is a ClickBank supplement with a 60-day money-back guarantee enforced at the platform level. Like NerveSoothe, its formulation is in a clinically plausible category — ALA and B vitamins for neuropathy support. The lower ClickBank gravity (approximately 0.2) does not indicate fraud; it indicates a newer or lower-volume product with less available market signal. Without extensive brand transparency data, we advise purchasing only through official ClickBank channels to ensure buyer protection is in place. If you purchase and are unsatisfied within 60 days, you can claim a refund through ClickBank regardless of what the vendor says.
For Deeper Reading
If you want to go deeper on any aspect of this comparison, these additional resources may help:
- NerveSoothe Review 2026: Full Ingredient and Effectiveness Analysis
- NerveSoothe Price Guide 2026: Best Deals and Bundle Comparison
- NerveSoothe: Scam or Legit? What the Evidence Actually Says
- Best Neuropathy Supplements for Diabetic Nerve Pain: 2026 Roundup
- Diabetic Neuropathy: Symptoms, Causes & Natural Treatment Options
- Nerve Armor vs NerveSoothe: Another Close Comparison
- Nerve Armor Review: Ingredients, Evidence & Verdict
- Diabetic Nerve Pain Home Remedies: What Folk Wisdom Gets Right
- Neuropathy No More Review: Is the Program Worth Trying?
Learn more about who we are on our About page, or read our disclosure for information on how we cover products on this site.
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Medical Disclaimer: The information in this article is provided for educational and informational purposes only. It is not intended as medical advice and should not be construed as a substitute for professional medical consultation, diagnosis, or treatment. Diabetic peripheral neuropathy is a serious medical condition that requires management by a qualified healthcare provider. Nutritional supplements are not approved by the FDA to treat, cure, or prevent any disease. Individual results from supplementation vary. Always consult your physician or other qualified healthcare professional before starting any supplement, particularly if you are managing diabetes, taking prescription medications, or experiencing worsening neuropathy symptoms. Statements about specific supplement formulations have not been evaluated by the Food and Drug Administration.